Research Fellow in Computational Structural Biology
Overview
The School of Biosciences at the University of Birmingham has a Research Fellow position in computational structural biology, in the group of Prof Teresa Carlomagno. The group studies the structure and function of proteins, intrinsically disordered proteins, membrane proteins, nucleic acids and their complexes with an integrative approach that combines experimental and computational methods, aiming to understand biomolecular structure, dynamics and function at atomic resolution.
The postholder will apply advanced computational methods to membrane proteins, protein-ligand complexes and biologically relevant macromolecular assemblies, focusing on molecular recognition, conformational dynamics, allosteric regulation and ligand binding. They will integrate computational models with experimental data from X-ray crystallography, NMR spectroscopy, cryo-electron microscopy, mass spectrometry and biophysical measurements, while developing new computational methods and modelling strategies. Duties include developing research objectives and proposals, generating and interpreting computational data, applying advanced molecular dynamics, creating new workflows and models, presenting findings at seminars and conferences, writing manuscripts, supervising students and contributing to funding applications.
Requirements
Candidates need a PhD, or be near completion, in computational structural biology, biophysics, structural biology, computational chemistry, biochemistry, physics or a related field. Strong expertise is expected in molecular dynamics simulations and enhanced-sampling methods such as metadynamics or accelerated molecular dynamics, together with advanced analysis of simulation data, including dimensionality reduction, conformational landscape analysis and identification of metastable states. Experience in multiscale modelling is highly desirable. Candidates should have experience with membrane proteins or protein-ligand complexes, a record of peer-reviewed publications, strong quantitative and communication skills, and the ability to work independently and in multidisciplinary international teams. Practical biochemical laboratory experience is desirable.
What you get
The full-time, fixed-term post has a normal starting salary of £36,636 to £46,049, with potential progression once in post to £48,822. Applications are welcome from candidates in Europe and other overseas countries, and financial support for visa application fees is available subject to eligibility and policy. The university is open to discussing flexible working.
How to apply
The full job description and online application are available through the university's recruitment pages. Informal enquiries can be made to Prof Carlomagno.
Key dates
The closing date is 19 October 2026.