Research Assistant/Associate

Overview

Newcastle University offers a full-time, fixed-term position as a Research Assistant or Research Associate within the Newcastle CRUK Drug Discovery Group. The role is part of an 18-month project funded by CRUK that aligns with the group's translational program, focusing on the validation of emerging drug targets in squamous cancers. The position runs until April 30, 2028, with the possibility of extension, and has a scheduled start date of January 2027. Work is conducted on site.

What you get

The salary is £34,630 to £39,560 per annum, with the Research Assistant position ranging from £34,630 to £36,320 per annum, and the Research Associate position ranging from £37,369 to £39,560 per annum. The role provides an opportunity to gain experience in the translational pathway from target identification to therapeutic development through collaboration with academic and drug discovery experts.

Who can apply

Applicants need a strong background in cancer cell signalling, experience with modern genetic manipulation techniques, and an interest in applying these approaches within a multidisciplinary drug discovery environment.

Requirements

Candidates must design, develop, and deploy genetic and pharmacological strategies to investigate target function and therapeutic potential. This involves using tool compounds, RNAi, CRISPR-mediated gene editing, and inducible degron systems in human tumour cell models. Responsibilities also include analysing molecular and cellular responses, identifying pharmacodynamic biomarkers, evaluating target dependency, conducting research with defined milestones, and contributing to drug discovery decision-making.

How to apply

Applications require a CV and a cover letter of no longer than 2 pages highlighting relevant experience for the post.

Key dates

The closing date for applications is November 20, 2026. Applications will be assessed by a panel, and in-person interviews will take place during the week commencing the first week of December. The starting date for the position is January 2027.