Research Fellow in Structural Biology (CryoEM)

Overview

The University of Leeds is hiring a Research Fellow in Structural Biology (CryoEM) within the Faculty of Biological Sciences, School of Molecular and Cellular Biology. This fixed-term role is available for 18 months to complete specific time-limited work investigating how proteins aggregate into amyloid fibrils and how these structures perturb cellular function. The successful candidate will work in the laboratories of Professors Sheena Radford and Neil Ranson on the main campus in Leeds, collaborating with Professor Raz Jelinek at Ben Gurion University.

Who can apply

Candidates should hold a PhD, or be close to completing one, in Structural Biology, Biochemistry, or a related discipline. Applicants are required to have an established background and extensive experience in using cryoEM to address questions regarding protein structure, assembly, and biological mechanisms.

What you get

The position offers a salary between £41,064 and £48,822 per annum on a full-time, fixed-term contract. Additional benefits include 26 days of holiday plus approximately 16 bank holidays and custom University closure days, generous pension scheme options with life assurance, and access to health and wellbeing services featuring discounted gym memberships at The Edge. Staff also receive access to professional development courses, on-site childcare, shopping discounts, and travel schemes.

Requirements

The role requires conducting cryoEM investigations, supported by other biochemical and biophysical analyses, to determine the structure of amyloid fibrils formed in vitro and purified from patient samples. Researchers will also evaluate the activity of different fibril types in causing neuronal dysfunction to understand how mutations and post-translational modifications affect amyloid aggregate formation and cellular function.

Key dates

The application closing date is 25 November 2026.